クロモジ熱水抽出物のコロナウイルスOC43に対する感染抑制作用
薬理と治療, 50(2): 195-201, 2022
Author: 河原岳志, 芦部文一朗, 松見 繁

 

Lactobacillus crispatus strain KT-11 S-layer protein inhibits rotavirus infection
Frontiers in Microbiology, 13: 783879, 2022
Author: Kawahara, T., Shimizu, I., Tanaka, Y., Tobita, K., Tomokiyo, M., Watanabe, I.

 

Anti-degranulatory and bile acid-binding activity of extracts prepared from fruits and agro-industrial by-products
Food Bioscience, 43: 101244, 2021
Author: Hamauzu. Y., Kawahara. T.

 

Inhibitory effect of strawberry geranium (Saxifraga stolonifera) on Toll-like receptor 2-mediated inflammatory response in human skin keratinocytes
Journal of Ethnopharmacology, 275: 114039, 2021
Author: Kawahara, T., Ito, A., Kiso. A., Kuwamoto. F.

 

Metabolomic evaluation of different starter culture effects on water-soluble and volatile compound profiles in nozawana pickle fermentation
Food Chemistry: Molecular Sciences, 2(30): 100019, 2021
Author: Tomita, S., Watanabe, J., Kuribayashi, T., Tanaka, S., Kawahara, T.

 

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クロモジ熱水抽出物のインフルエンザウイルス感染抑制メカニズムの検討
薬理と治療, 48(8): 1357-1371, 2020
Author: 河原岳志, 芦部文一朗, 松見 繁, 丸山徹也


Lactobacillus plantarum Shinshu N-07 isolated from fermented Brassica rapa L. attenuates visceral fat accumulation induced by high-fat diet in mice
Beneficial Microbes, 11(7): 655-667, 2020
Author: Yin, T., Bayanjargal, S., Fang, B., Inaba, C., Mutoh, M., Kawahara, T., Tanaka, S., Watanabe, J.


Suppressive effects of hot-water extract of Magnolia obovata on Clostridium perfringens enterotoxin-induced cytotoxicity in human intestinal Caco-2 cells
Planta Medica, 86(3): 198-204, 2020
Author: Kawahara, T., Fujii, K., Nakajima, K., Fujii, R., Inagaki, S., Yasui, H.


クロモジ熱水抽出物の持続的なインフルエンザウイルス増殖抑制効果
薬理と治療, 47(8): 1197-1204, 2019
Author: 河原岳志, 芦部文一朗, 松見 繁, 丸山徹也


Characterization of microbiota that influence immunomodulatory effects of fermented Brassica rapa L.
Microbes and Environments, 34(2): 206-214, 2019
Author: Sandagdorj, B., Hamajima, C., Kawahara, T., Watanabe, J., Tanaka, S.


Effect of Lactobacillus strains on thymus and activation-regulated chemokine expression in keratinocytes and the development of atopic dermatitis-like symptoms
Beneficial Microbes, 9(4): 643-652, 2018
Author: Kawahara, T., Hanzawa, N., Sugiyama, M.


Effect of the topical application of an ethanol extract of quince seeds on the development of atopic dermatitis-like symptoms in NC/Nga mice
BMC Complementary and Alternative Medicine, 17(1): 80, 2017
Author: Kawahara, T., Tsutsui, K., Nakanishi, E., Inoue, T., Hamauzu, Y.


Effect of oral administration of the IgE-suppressive wild yeast strain Saccharomyces paradoxus P01 on the development of atopic dermatitis-like symptoms in NC/Nga mice
Food Science and Technology Research, 21(2): 223-230, 2015
Author: Kawahara, T., Nakayama, D., Tanaka, K., Yasui H.


Inhibitory effect of a hot-water extract of Japanese big-leaf magnolia (Magnolia obovata) on rotavirus-induced diarrhea
Evidence-Based Complementary and Alternative Medicine, 2014:365831, 2014
Author: Kawahara, T., Tomono, T., Hamauzu, Y., Tanaka, K., Yasui, H.

Suppressive effect of wild Saccharomyces cerevisiae and Saccharomyces paradoxus strains on IgE production of mouse spleen cells
Food Science and Technology Research, 19(6): 1019-1027, 2013
Author: Kawahara, T., Nakayama, D., Toda, K., Inagaki, S., Tanaka, K., Yasui, H.

 

Establishment and characterization of mouse bone marrow-derived mast cell hybridomas
Experimental Cell Research, 318(18): 2385-2396, 2012
Author: Kawahara, T.

Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells
Cytotechnology, 63(2): 143-152, 2011
Author: Kawahara, T., Iizuka, T.

 

Inhibitory effect of fermented grape pomace on degranulation in RBL-2H3 cells and an analysis of its active ingredient
Food Science and Technology Research, 17(3): 241-250, 2011
Author: Kondo K., Nakamura K., Hamauzu Y., Kawahara T., Sansawa, H., Suzuki, M., Yasui, H.


Characterization of the bacteriocinogenic lactic acid bacteria Lactobacillus curvatus strain Y108 isolated from Nozawana-zuke pickles
Food Science and Technology Research, 16(3): 253-262, 2010
Author: Kawahara, T., Iida, A., Toyama, Y., Fukuda, K.

 

Inhibitory effect of heat-killed Lactobacillus strain on immunoglobulin E-mediated degranulation and late-phase immune reactions of mouse bone marrow-derived mast cells
Animal Science Journal, 81(6): 714-721, 2010
Author: Kawahara, T.

Anti-allergic effect of a hot-water extract of quince (Cydonia oblonga)
Bioscience, Biotechnology, and Biochemistry, 73(8): 1773-1778 2009
Author: Shinomiya, H., Hamauzu, Y., Kawahara, T.

 

Inhibitory effect of electrolyzed reduced water on tumor angiogenesis
Biological & Pharmaceutical Bulletin, 31(1): 19-26, 2008
Author: Ye, J., Li, Y., Hamasaki, T., Nakamichi, N., Komatsu, T., Kashiwagi, T., Teruya, K., Nishikawa, R., Kawahara, T., Osada, K., Toh, K., Abe, M., Tian, H., Kabayama, S., Otsubo, K., Morisawa, S., Katakura. Y., Shirahata, S.


Catalyser-21™, a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis
Cytotechnology, 55(2-3): 61-70, 2007
Author: Ye, J., Li, Y., Hamasaki, T., Nakamichi, N., Kawahara, T., Osada, K., Teruya, K., Kato, Y., Toh, K., Abe, M., Katakura, Y., Noguchi, K., Shirahata, S.


Oral ingestion of phosphorylated dextrin stimulates antibody responses in mice
Journal of Nutritional Science and Vitaminology, 53(4): 354-357, 2007
Author: Otani, H. Morimoto, T., Kawahara, T.


Stimulatory effect of lactic acid bacteria from commercially available pickle "Nozawana-zuke" on cytokine expressions of mouse spleen cells
Bioscience, Biotechnology, and Biochemistry, 70(2): 411-417, 2006
Author: Kawahara, T., Otani, H.


Cow's IgG1 and its proteolytic digests stimulate immunoglobulin formation in mouse spleen cell culture
Milchwissenschaft, 62(1): 9-12, 2006
Author: Mizutani, A., Ohnuki, H., Kawahara, T., Otani, H.


Bovine β-casein (1-28), a casein phosphopeptide, enhances proliferation and IL-6 expression of mouse CD19+cells via Toll-like receptor 4.
Journal of Agricultural Food Chemistry, 54(21): 8013-8017, 2006
Author: Tobita K, Kawahara T, Otani H.


IL-12誘導活性を示す天然葉緑土由来ミネラル水中の複合糖質の構造解析
分析化学, 54(5): 391-397, 2005
Author: 加藤祐子，太田雅也，亀井恭平，脇田久伸，河原岳志，山野 雄一郎，濱崎 武記，照屋 輝一郎，長田和浩，西川竜平，野口克己，白畑實隆


ガン特異的ヒト型モノクローナル抗体の取得
信州大学農学部紀要, 41(1-2): 7-14, 2005
Author: 河原岳志

Effect of bovine κ-caseinoglycopeptide on mitogen-induced proliferative responses of spleen cells from different strains of mice
Milchwissenschaft,60(3): 245-248, 2005
Author: Otani, H., Horimoto, Y., Matin, M.A., Ohnuki, H., Kawahara, T.


Characterization of casein phosphopeptides from fermented milk products
Journal of Nutritional Science and Vitaminology, 51(5): 377-381, 2005
Author: Kawahara, T., Aruga, K., Otani, H.


Stimulatory effect of a casein phosphopeptide (CPP-III) on mRNA expression of cytokines in Caco-2 cells
Bioscience, Biotechnology, and Biochemistry,68(8): 1779-1781, 2004
Author: Kawahara, T., Otani, H.


Effect of β-casein (1-28) on proliferative responses and secretory functions of human immunocompetent cell lines
Bioscience, Biotechnology, and Biochemistry, 68(10): 2091-2095, 2004
Author: Kawahara, T., Katayama, D., Otani, H.


Stimulatory effect of a dietary casein phosphopeptide preparation on the mucosal IgA response of mice orally ingested lipopolysaccharide from Salmonella typhimurium
Bioscience, Biotechnology, and Biochemistry, 67(4): 729-735, 2003
Author: Otani, H., Nakano, K., Kawahara, T.


Protective mechanism of reduced water against alloxan-induced pancreatic β-cell damage; Scavenging effect against reactive oxygen species
Cytotechnology, 40(4): 139-149, 2002
Author: Y.P. Li., Nishimura, T., Teruya, K., Maki, T., Komatsu, T., Hamasaki, T., Kashiwagi, T., Kabayama, S., Shim, S.-Y., Katakura, Y., Osada, K., Kawahara, T., Otsubo, K., Morisawa, S. Ishii, Y., Gadek, Z., Shirahata S.


Role of tachylectins in host defense of the Japanese horseshoe crab Tachypleus tridentatus
Advances in Experimental Medicine and Biology, 484: 195-202, 2001
Author: Kawabata, S., H. G. Beisel., Huber, R., Bode, W., Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S. N., Iwanaga, S.


Establishment of hybridomas producing cancer specific human antibodies from B cell line derived from PBL of a patient with adult T cell leukemia
Cytotechnology, 36(1-3): 171-177, 2001
Author: Kawahara, T., Ichikawa, A., Katakura, Y., Teruya, K., Yoshida, T., Kikuchi, M., Hashizume, S., Shirahata, S.


Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen
Proceedings of the National Academy of Sciences of the U.S.A., 96(18): 10086-10091, 1999
Author: Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S.N., Iwanaga, S., Kawabata, S.